ALLOWABLE VITAMIN POTENCY UNDER CODEX: Vitamin C (225 mg - up from the original 60 mg); Vitamin E (15 mg - up from the original 7)(Gamma Tocopherol); Magnesium (400 mg); Vitamin B-12 (9 mcg when normal dose in the 1940s-70s was 2400-2800 daily and we had very little dementia); Vitamin B-6 (5.4 mg - when we know a minimum of 200 mg daily is for basic intake); Beta Carotene (4 mg); Vitamin D (5 mg - although FDA is currently suggesting a minimum of 1000 mg)
A supplement composed of vitamins B-1, B-3, B-6, B-12, C, D, E, folic acid, beta-carotene, CoQ10, rutin, bioflavonoids, ginkgo biloba, ginseng, green tea extract, ginger root extract, garlic, L-Glutathione, magnesium, selenium, potassium, manganese, chromium picolinate, acetyl L-carnitine, melatonin, alpha-lipoic acid, N-acetyl cysteine, acetylsalicylic acid, cod liver oil and flax seed oil supports anti-aging.Much of this research has been completed in the past by such natural health greats as Gary Null, Carleton Fredericks, and Gayelord Haueser. In the 40-50-60s vitamins, especially B complex and B12, along with natural thyroid support were key medical therapies for aging and prevention of dementia.
A cocktail of vitamins, minerals and herbals may delay the major aspects of the aging process and extend lifespan by 10%, according to a mouse study from Canada led by David Rollo.
Mice fed a supplement containing 30 dietary ingredients did not experience a 50% loss in daily movement like non-supplemented animals, according to findings published in the journal Experimental Biology and Medicine.
The benefits were linked to increases in the activity of mitochondria, the power plants of the cells, as well as by reducing levels of free radicals produced by the mitochondria, said researchers from McMaster University.
"For aging humans, maintaining zestful living into later years may provide greater social and economic benefits than simply extending years of likely decrepitude," Rollo said. "This study obtained a truly remarkable extension of physical function in old mice, far greater than the respectable extension of longevity that we previously documented. This holds great promise for extending the quality of life of humans," he added.
Rollo and his co-workers used bradykinesis, or declining physical movement, as a biomarker of aging and mortality risk. Mice were divided into two groups: One was fed a normal diet, while the other was supplemented with a cocktail of dietary supplement ingredients.
"Dosages were derived from recommended human doses adjusted for body size and the 10-fold higher metabolic rate of mice," explained the researchers.
Results showed maintenance of youthful levels of locomotor activity into old age in the supplemented animals, whereas old non-supplemented mice showed a 50% loss in daily movement, said the researchers. This was accompanied by a loss of mitochondria activity, and declines in brain signaling chemicals relevant to locomotion, such as striatal neuropeptide Y. This chemical is associated with a range of functions, including maintaining energy balance, as well as effects in memory and learning. No such declines were observed in supplemented animals, the researches said.
"Although identifying the role of specific ingredients and interactions remains outstanding, results provide proof of principle that complex dietary cocktails can powerfully ameliorate biomarkers of aging and modulate mechanisms considered ultimate goals for aging interventions," Rollo and his co-workers stated.
The supplement was composed of vitamins B-1, B-3, B-6, B-12, C, D, E, folic acid, beta-carotene, CoQ10, rutin, bioflavonoids, ginkgo biloba, ginseng, green tea extract, ginger root extract, garlic, L-Glutathione, magnesium, selenium, potassium, manganese, chromium picolinate, acetyl L-carnitine, melatonin, alpha-lipoic acid, N-acetyl cysteine, acetylsalicylic acid, cod liver oil and flax seed oil.
Experimental Biology and Medicine 235:66-76, 2010
Personality may influence brain shrinkage in aging
ScienceDaily (2010-04-27) -- A team of psychologists has found an intriguing possibility that personality and brain aging during the golden years may be linked. Researchers found lower volumes of gray matter in the frontal and medial temporal brain regions of volunteers who ranked high in neuroticism traits, compared with higher volumes of gray matter in those who ranked high in conscientious traits. ... > read full article