I would like everyone to consider the view of my esteemed colleague, Steve Shackel of Australia.
He is a person living with ALS and has an amazingly in depth web site with a great amount of science backed data.
My early research was into B3. I met my first bona fide mad professor, who was convinced B3 deficiency was responsible for all neurodegenerative illnesses. He made many good points but as my research progressed I concluded that it was not a B3 deficiency so much as the ability to metabolise B3 in therapeutic quantities that was the problem. I could go on...
I'll update my info and provide a link to this (more recent) research. Thanks for forwarding it to me. All these things help to fill out the big picture!
And to further this position I am adding some additional data for your benefit -
REF: Vitamin B12: Vital Nutrient for Good Health
REF: High-dose vitamin B12 for at-home prevention and reversal of Alzheimer's disease and other diseases
REF: Vitamin C, E, Selenium
Daniel Fabricant, Ph.D., writes about the JAMA study denouncing the benefit from Vitamins C and E. Fabricant comments concerning flaws in the study which have altered the results and reliability of the study in question:
“On the second page of the study, it references nine pooled studies that when using 700 milligrams per day of vitamin C showed a 25-percent reduction in the occurrence of cardiovascular disease (CVD); yet this study only used 500 milligrams per day. Why wasn't the 700 milligrams per day amount used when that has been correlated with a reduction in occurrence in prior studies?
“Additionally, while the study did control for multivitamin intake to prevent overlap, intake of vitamin C and E from food was not controlled. With a population of health care professionals at an increased risk for CVD, these subjects most likely know the benefits of a diet rich in fruits and vegetables, and thus rich in vitamins C and E, and may adjust their intake accordingly. This would most certainly confound the study.
“It is essentially a drug study but one without a positive control, which is necessary to ensure the experimental design can produce a positive result even if the intervention was unable to.”