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Showing posts with label osteoporosis drugs. Show all posts
Showing posts with label osteoporosis drugs. Show all posts

Tuesday, February 28, 2012

Most Taking Rx for Bone Drugs Quit

Certainly this is no surprise.  Osteoporosis drugs have many problematic and even life threatening side effects. They also require many lifestyle adjustments that after time many people, both men and women, find difficult.  Additionally many are fluoride based which causes the reduction or even ending of the function of osteoclast cells in your body.  Many severe fractures and jaw bone problems are linked to this drug function.



There are more natural things you can do to protect bone health.  And there are many natural approaches to keeping them strong and healthy.


Walking and weight bearing exercise are great!  Learn Tai Chi. Look into Lymphology at IAL.


A healthy diet and the right supplements are great! (Just don't be taking so much calcium.  Generally doctors tell you to take about twice what you need and the wrong type - carbonate).


Get hydrated!


Cut down on exposure to EMF and fluoride as well as other environmental toxins (the DEXA test is one of these and so is your cell phone).


Consider drinking nettle tea.


Consider using homeopathic cell salts.


Get tested for and take vitamin D3. (25 OH test)


Watch soy, it can block calcium, and is too often GMO.


Susan Brown PhD has been writing on this subject for years. Check out her book, Better Bones.
By Frederik JoelvingNEW YORK | Mon Feb 27, 2012 5:27pm EST(Reuters Health) - People with the bone-thinning condition osteoporosis often skip the drugs they are prescribed, and telephone counseling does little to change that, according to new research.
Researchers said osteoporosis is involved in more than two million fractures a year in the U.S., racking up medical costs of $19 billion.
In addition to exercise and a healthy diet with enough calcium and vitamin D, as well as measures to prevent falls, medications may reduce the risk of broken bones -- which can take a serious toll on the health of old people.
For people at high risk, bone drugs such as bisphosphonates may cut the yearly fracture risk from five percent to three percent, said Dr. Daniel Solomon of Brigham and Women's Hospital in Boston.
But people often stop taking the medications, added Solomon, also of Harvard Medical School.
"It's the problem with all chronic conditions," he told Reuters Health. "Drugs for asymptomatic chronic conditions are universally poorly adhered to."
Some 10 million Americans currently suffer from bone thinning, according to the National Osteoporosis Foundation. The majority are postmenopausal women.
Bone drugs include Merck's Fosamax, Roche's Boniva, Novartis's Reclast and Warner Chilcott's Actonel.
To see if they could convince people to take their drugs, Solomon and his colleagues divided more than 2,000 men and women with osteoporosis into two groups.
The participants were all on Medicare, the government's health insurance for the elderly, and got their meds for a co-pay of no more than a few dollars.
All of them received fall-prevention lifestyle tips in the mail from the researchers, and one group also had about eight counseling sessions over the phone.
During those sessions, trained counselors tried to identify why people skipped their drugs and to motivate them to get back on the treatment. The intervention ended up costing about $281 per patient, including training of the counselors.
After one year, there was little difference between the two groups.
Those who got counseling filled their prescriptions 49 percent of the time, while the others did so 41 percent of the time, based on claims data. That gap was too small to be reliable, statistically speaking.
The researchers didn't find any differences in how many people broke a bone or reported falls, either.
According to Solomon, people who skipped their medicine often said they had forgotten about it, didn't like the way it made them feel or didn't think they needed it.
Still, Solomon, whose findings appear in the Archives of Internal Medicine, wasn't willing to give up on counseling.
"It would be overstating the data to say that we should use this. What I'm saying is you don't want to throw the baby out with the bathwater," he said. "I think that counseling is something we need to continue to examine."
Researchers have been experimenting with a lot of ways to get people to take their drugs, including beeping pill caps and financial incentives, Solomon added. But the results have often been disappointing.
"At this point there really aren't any proven interventions," he said.
In an editorial, Dr. Seth Berkowitz and Dr. Kirsten Johansen of the University of California, San Francisco, say behavior change is an increasingly important part of medicine as chronic diseases continue rise.
"There is likely no 'magic bullet' in the behavior change arsenal in general or for increasing treatment adherence specifically," they write. "This does not mean, however, that the effects may not be clinically significant."
SOURCE: bit.ly/yMrnv4 Archives of Internal Medicine, February 27, 2012.
Selections from over 30 on Natural Health News

Feb 18, 2012
Osteoporosis drugs have many drawbacks. The same drugs have many risks including the risk of very bad fractures and having your jaw bone eaten away (necrosis). For the most part the drugs are fluoride based and cause ...
Dec 27, 2011
Researchers asked if “real-world” patients taking bone drugs received the same fracture-reduction benefits seen in the clinical trials. After analysis of hundreds of studies, they found that highly compliant, “real world” patients ...
Feb 03, 2010
New results from a landmark women's health study raise the exciting possibility that bone-building drugs such as Fosamax and Actonel may help prevent breast cancer. Women who already were using these medicines when ...
Nov 18, 2008
Bone Loss Problematic, Bone Drugs Risky. In January 2008 the FDA issued warnings regarding the class of drugs developed to allegedly help people with osteopenia and osteoporosis. Numerous problems are associated ...

Tuesday, December 27, 2011

How big is the bang from osteoporosis drugs?

From Susan Brown, PhD



Answering the question “how big is the bang from osteoporosis drugs?” can be quite challenging.
One reason is that the statistical calculations are complex and highly manipulated making them difficult to understand. Another is that the subjects included in the drug studies are generally highly-selected and may not represent “real-world” populations.
Recently scientists took an important step to help us separate hype from reality in regard to the benefits of bone drugs.
Researchers asked if “real-world” patients taking bone drugs received the same fracture-reduction benefits seen in the clinical trials. After analysis of hundreds of studies, they found that highly compliant, “real world” patients on osteoporosis drugs experienced a 21% reduction in all clinical fractures. This compares to the 24% overall clinical fracture reduction experienced by subjects in osteoporosis drug clinical trials.
What a different messages than we often hear — such as how bone drugs reduce your chance of fracture by 50%! Or have you ever been told that the fracture reduction on bone drugs is really more like 21-24%? That is — if you use the drug faithfully.
Now compare this 21-24% fracture-reduction benefit from bone drugs to the studies documenting that those taking vitamin D in any dose (much less a therapeutic dose) experience a 23-26% reduction in fractures. It seems to me that the bang from osteoporosis drugs isn’t quite as big as we’ve been led to believe.
As your bone health advocate, I congratulate these researchers on the enormous effort to analyze and synthesize data from hundreds of studies. I also congratulate the drug company which funded this study for clarifying the real fracture/reduction benefit of today’s bone drugs.

References:
Wilkes, et al. 2010. “Bisphosphonates and osteoporotic fractures: a cross-design synthesis of results among compliant/persistent postmenopausal women in clinical practice versus randomized controlled trials.” Osteoporosis International 21:679-688
Bischoff-Ferrari, HA et al. 2005. Fracture prevention with vitamin D supplementation: A meta-analysis of randomized controlled trials. JAMA, 293(18): 2257-2264

The Week in Bone Health | How big is the bang from osteoporosis drugs?


Selections from Natural Health News

Sep 06, 2011
The osteoporosis drug zoledronic acid (Reclast) should not be used in patients with significant renal impairment, and physicians should screen patients for kidney dysfunction before starting them on the drug, the FDA said. ...
Aug 16, 2009
Another Big PhARMA fiasco, as all the current osteoporosis drugs seem to be. Of course you don't hear too much about their fluoride content and how this damages the thyroid and bone health, but then how would they mask ...
Oct 02, 2009
Osteoporosis drug Forteo linked with bone cancer. BLACK BOX WARNING FOR FORTEO, a gentically engineered pharmaceutical. POTENTIAL RISK OF OSTEOSARCOMA: In male and female rats, teriparatide caused an ...
Jan 24, 2009
***Just remember that as bone density leads to brittle bones and fracture, so do the prescription osteoporosis drugs. ... Part of this missing link is the bone-damaging impact from many non-osteoporosis drugs. Another is that ...

Tuesday, September 06, 2011

More about risky drugs and Osteoporosis

UPDATE: 9/10/11
Another new article points to the insanity of the FDA's process of approving drugs that take so long to report data about the risk to bone health.  The other odd consideration is the lack of attention to how to properly label problematic drugs and how to determine just how long someone would take a risky Rx.
FDA advisers wary of time limit on bone drugs

From 9/6/11
Today it was announced that Blythe Danner, actress and mother of Gwyneth Paltrow, has osteoporosis. 

The article states "In order to spread awareness about osteoporosis, Danner is helping launch Act2ReduceFractures.com, an informational Web site on fracture risk jointly sponsored by Amgen, American Bone Health, the Global Healthy Living Foundation, and the Older Women’s League."

This is of course another celebrity pushing drugs and avoiding any discussion of what natural remedies are available to help prevent and treat bone loss. Fluoride based drugs with many serious adverse reactions are the cornerstone along with low level dosing of vitamin D, calcium, and kale chips which are in fact quite good.

Nothing is referenced about the problems with calcium about the form and utilization as well as the need for a full complement of nutrients to keep bones strong and healthy.

No mention of herbs, no mention of homeopathy, no mention of many good natural approaches.
Read complete article

Also consider this - 

Thursday September 01, 2011
Reclast Gets FDA Kidney Failure Warning 
The osteoporosis drug zoledronic acid (Reclast) should not be used in patients with significant renal impairment, and physicians should screen patients for kidney dysfunction before starting them on the drug, the FDA said.
http://www.medpagetoday.com/ProductAlert/Prescriptions/28320?utm_source=breaking-news&utm_medium=email&utm_campaign=breaking-news

Look to Health Forensics for more information 


Selections from Natural Health News

Aug 16, 2009
Osteoporosis involves the thinning of bones, and if some measures are not taken, it can lead to excruciating pain accompanied by fractures and forms of disability. For treatment, one should take proper intake of ...
Aug 12, 2009
FDA staff has expressed concerns that denosumab, the investigational biologic drug for osteoporosis, may increase risk of serious infections through its activity against an important immune system modulator. ...
Jun 05, 2006
more than just osteoporosis - Further down in this post you will find this paragraph:"Oncologist Julie Gralow, M.D., of the University of Washington and Fred Hutchinson Cancer Center in Seattle said that women should ...
Oct 02, 2009
The first case of osteosarcoma associated with Forteo use was published in the Journal of Bone Mineral Research in 2007 (JBMR vol. 22, p. 334), and a second case was published on-line in Osteoporosis International on the ...

Monday, March 08, 2010

Diane Sawyer, ABC News and FDA very late in reporting on bone drug problems

Regarding soda, see this post

UPDATE: MARCH 28 - HEALTH EFFECTS: Fluoride & Osteoblasts
Fosamax Induced Fractures, More Bad News 
As if Fosamax didn't have enough problems, another nail was hammered into the coffin at the 2010 AAOS Meeting. Two more studies came out showing Fosamax disturbs bone formation, and implicates Fosamax in spontaneous mid-femur fractures (without trauma). These reports came from the Hospital for Special Surgery (HSS) and Columbia University Medical Center. 

Fosamax Study Denies Link with Femur Fractures - A recent NEJM article by Dennis Black MD denying a link between Fosamax and spontaneous mid-femur fractures has many doctors raising their eyebrows.  Firstly, there is the problem of conflict of interest.  The study was funded by Fosamax maker, Merck, and the authors are all on Merck's payroll.
UPDATE: 27 March 2010 -


Pharma and New York Times are “Puzzled” by Bone Drug Fractures–But Patients Aren’t

ORIGINAL POST:  Dating back to 2006 and earlier you will find many articles here on the risks on bone health issues when using the Big PhRMA osteoporosis drugs.

It is very critical that you understand that the bisphosphonate drugs are associated with killing off specific cells that have to do with the complete cycle of bone construction and destruction in the body's natural physiology.

Another critical issue is the fluoride base in the majority of these drugs, known to cause the creation of brittle bones or what is called "swiss cheese" or weak bones that cannot stand up to stress. Many other drug classifications, such as antibiotics and antidepressants, that contain fluoride compounds will also promote negative bone health issues.

You can locate our prior articles on this topic using the search box at the top of the right column.

Please feel free to contact us for your consultation about what you can do naturally to have strong, healthy bones. It isn't by using Fosamax or any of the other osteoporosis Rx drugs.

This article identifies many of the problems caused by fluoride.

Should you have legal concerns, perhaps our legal colleagues at Chaffin Luhana LLP may be able to assist you if you have suffered fracture from using these drugs.

Bone Drugs Risky

Fluoride in Fosamax, Reclast

Halogens

And in this new report learn about visual problems with the use of anti-depressants (SSRI fluoride based compounds) -
Anti-depressants bring higher risk of developing cataracts

ScienceDaily (2010-03-08) -- Some anti-depressant drugs are associated with an increased chance of developing cataracts, according to a new statistical study. ... > read full article
Seems there must be something prescribers are not telling those to whom they give these drugs!
FLUORIDE ALERT: Please drop everything you are doing and watch the TV news story, "Dangerous Fluoride," from the CBS affiliate in Atlanta, Georgia at http://www.cbsatlanta.com/video/22781769/

Remember Atlanta is the home of the CDC: the biggest promoter of fluoridation in the US and the world. Dan Stockin has struck at the heart of the beast of fluoridation in its home town. Neither the ADA nor the CDC could provide answers to the CBS news team. Source:FLUORIDE ACTION NETWORK http://www.FluorideAlert.Org