AddThis Feed Button "Frequently Copied, Never Duplicated"

Showing posts with label vitamin B6. Show all posts
Showing posts with label vitamin B6. Show all posts

Tuesday, October 11, 2011

VITAMINS HAVE NEVER KILLED ANYONE

I am sure everyone is buzzing about the fallacious news stories from the last couple of days that are telling you taking vitamins is risky for your health.  Every time I hear reports on these studies I get mad.  I get more so when I hear the local ABC outlet news anchor say she does fair and balanced reporting.
If her reporting was fair and balanced she would include the following information from Mitch Stargrove an ND I have known over some years:
It is not advisable to make a causal statement of excess risk based on these observational data..." Without proper accounting of and informed choices for form, dose, combination, sequencing of nutrients this data says little of clinical consequence. Moreover, the fundamental premise of natural medicine is personalized and evolving care in concert with a healthcare professional trained and experienced in nutritional therapies. All contemplated supplement usage should be discussed with primary care providers, such as (licensed) naturopathic physicians, who are trained in their appropriate, prudent and proper usage. Lastly, reliance of foods, i.e., fruits and vegetables, is not what it used to be. Solid research shows that the nutrient content of commercially grown foods sold in the USA has declined markedly over the past 30 years; presumably due to industrial/petrochemical agribusiness practices and priorities. Other problematic factors have been mentioned by previous responses to this alarmist declaration which reveals a hostile and prejudiced posture in the conventional medical world that does not serve the patient's best interests nor the methodology of science and discovery.


The only concern I have fore vitamins used by people over 40 is iron unless the person is clearly anemic.  Iron is known to be a higher risk of heart attack in this age group.


Zinc is important for immune support and endocrine health.  If elevated Copper is usually low.  Too much copper is a risk but reputable supplements know the safe limits.


Magnesium is good for the brain and nervous system just like the B vitamins.  Magnesium is usually deficient especially if you are using Rx drugs. 


Many forms of calcium are not well absorbed and yet this "study" tells you to take it.


If you need help deciding on your supplements we offer this service through our Health Forensics programs. Email us for more information.


I'll continue taking my vitamins, Thank you!


From Natural Products Insider


Then consider this from MedPage Today


Readers Say Vitamin Levels Should Be Checked Yearly

By Chris Kaiser

Cardiology Editor, MedPage Today
Published: October 07, 2011
Processed foods, mineral-depleted soil, overcooked vegetables, increased stress levels -- all of these increase the chances of having a vitamin deficiency, according to a vocal majority ofMedPage Today readers who commented on last week's poll.
We asked readers if and when patients should be assessed for vitamin deficiencies. Of the more than 2,200 votes, 69% said that patients' vitamin levels should be assessed at least annually.
"I cannot remember how many patients have been rescued from dementia and psychosis by B12, especially when I have a geriatric focus," said one doctor, who also touted vitamin D, calcium, fish oil, and thyroid testing. "Everybody deserves a look about once a year."
But once a year was not enough for some (9% said every visit) and too much for others. One cardiologist said he or she tests vitamin levels every six months with a "pick up rate over 25%." Another commenter said that yearly testing seems too frequent. "Getting a baseline every five years with additional testing as needed seems better."
We received several anecdotal accounts about vitamin deficiency being caught, but only when the patient requested the test.
"I was diagnosed with severe insufficiency of vitamin D and only had it tested because I requested it," said one woman, who added that her mother and daughter were subsequently found to be vitamin D-deficient.
"I have just been rescued from severely low vitamin D levels, and my daughter has been found to have low vitamin levels as well. I wish my doctors had been checking levels all along," noted another MedPage Today reader.
And another expressed similar exasperation. "It was not until I was diagnosed with osteoporosis that I had a vitamin D 25-OH test, and found out that despite being outside every day, my level was insufficient. By then it was too late. I am very disappointed that my physician did not order this inexpensive test years ago. Now, I have asked for a B12 test as well."
One woman's B12 deficiency mimicked multiple sclerosis and she went through a battery of tests before a neurologist ordered vitamin testing for her.
"It baffles me that insurance companies aren't pushing for annual vitamin testing, because so many conditions can be resolved with proper vitamin supplementation," wrote one woman, who also was found deficient in vitamin D after she requested the test.
The comments also parsed the meaning of "recommended daily allowance" (RDA). Most agreed that the RDA is not meant to prevent disease states but more to support optimum health.
"The original purpose of RDAs was to specify the amounts of various micronutrients needed by the 'average' person to guard against deficiency disease; the fact that a person does not have scurvy or anemia doesn't mean she/he is getting enough vitamin C or B12, respectively, to be as healthy as possible," wrote one commenter.
But what is the root cause of vitamin deficiency? "We need to start with nutrition," was how one physician simply put it.
Others, as well, chimed in with the notion that vitamin deficiencies and chronic diseases are symptoms of malnourishment, which is symptomatic of poor eating habits.
As expressed by one European, "Ultimately, there is simply no substitute for a healthy diet. Sadly, American diets often lean toward processed foods, which tend to be low in nearly every (micro)nutrient other than sodium."
"Healthy eating is almost nonexistent today," said another commenter. "Processed and modified foods simply are not as nutrient-dense as their counterparts were perhaps 20 years ago."
And, as usual, we had at least one post worthy of going in the X-file.
"I wonder how much this 'concern' is being driven by yet more EU 'directives' banning the sale of 'natural' additives and supplements," this commenter wrote. "Whilst the profession should remain wary of too close an 'association' with what is considered as 'Big Pharma,' we should also remain acutely aware of signs and symptoms of deficiencies which have been known and recognized for centuries. The prescribing decisions must always be made as a result of knowledge, not some bureaucratic nonsense from an invisible and unaccountable back-room mandarin with several bees in his bonnet and 'fees' to be earned!"

And now the meaningless study -


Dec 27, 2009
NEW YORK (Reuters Health) – An analysis of "real-world" clinical data indicates that vitamin E, and drugs that reduce generalized inflammation, may slow the decline of mental and physical abilities in people with Alzheimer's ...

Dietary Supplements Linked to Higher Death Risk

By Todd Neale, Senior Staff Writer, MedPage Today
Published: October 10, 2011
Reviewed by Zalman S. Agus, MD; Emeritus Professor
University of Pennsylvania School of Medicine and
Dorothy Caputo, MA, RN, BC-ADM, CDE, Nurse Planner
In postmenopausal women, the use of several common vitamin and mineral supplements was associated with an increased risk of death, researchers found.

After adjustment for multiple potential confounders, use of multivitamins and vitamin B6, folic acid, iron, magnesium, zinc, and copper supplements was associated with greater all-cause mortality through 19 years of follow-up (HRs 1.06 to 1.45), according to Jaakko Mursu, PhD, of the University of Eastern Finland in Kuopio, and colleagues.

Use of a daily calcium supplement, on the other hand, was associated with a lower risk of death (HR 0.91, 95% CI 0.88 to 0.94), the team reported in the Oct. 10 issue of the Archives of Internal Medicine.


"Based on existing evidence, we see little justification for the general and widespread use of dietary supplements," they wrote, citing a body of literature generally supporting no association with mortality, with some suggestions of harm. "We recommend that they be used with strong medically based cause, such as symptomatic nutrient deficiency disease."
"We cannot recommend the use of vitamin and mineral supplements as a preventive measure, at least not in a well-nourished population," they wrote. "Those supplements do not replace or add to the benefits of eating fruits and vegetables and may cause unwanted health consequences."
Taking dietary supplements to improve health and prevent diseases is widespread, with about half of U.S. adults using one or more in 2000, according to Mursu and colleagues. Annual sales top $20 billion.
The long-term impact of supplementation is unknown, however, and some studies have suggested a relationship between supplements and increased mortality.
As Rita Redberg, MD, of the University of California San Francisco, wrote in an editor's note, "manufacturers are not required to disclose to the FDA or to consumers the evidence they have regarding their products' safety, nor must they empirically back up claims of purported benefits."
In light of this uncertainty, Mursu and colleagues examined the use of vitamin and mineral supplements among 38,772 postmenopausal women participating in the Iowa Women's Health Study. The mean age of the women at baseline in 1986 was 61.6.
The participants reported their use of supplements in 1986, 1997, and 2004. The percentage who reported using at least one supplement daily increased from 62.7% to 85.1% during the study. In 2004, more than one-quarter of the women (27%) said they used four or more.
The most commonly used supplements were calcium, multivitamins, vitamin C, and vitamin E.
Through 2008, 40.2% of the women died.
After adjustment for demographics, dietary and lifestyle factors, comorbidities, and use of hormone replacement therapy, the following supplements were associated with a greater risk of death during follow-up:
  • Multivitamins: HR 1.06 (95% CI 1.02 to 1.10)
  • Magnesium: HR 1.08 (95% CI 1.01 to 1.15)
  • Zinc: HR 1.08 (95% CI 1.01 to 1.15)
  • Iron: HR 1.10 (95% CI 1.03 to 1.17)
  • Vitamin B6: HR 1.10 (95% CI 1.01 to 1.21)
  • Folic acid: HR 1.15 (95% CI 1.00 to 1.32)
  • Copper: HR 1.45 (95% CI 1.20 to 1.75)
Absolute increases in risk ranged from 2.4% with multivitamins to 18% with copper.
After multivariate adjustment, use of calcium supplementation was associated with a lower risk of death (HR 0.91, 95% CI 0.88 to 0.94). The absolute risk reduction was 3.8%.
To account for the multiple comparisons made, however, the researchers set a P value of less than 0.003 to establish significance. Only the increase associated with multivitamins, calcium, and copper remained significant using this threshold.
"However, many of the additional statistical tests were confirmatory, strengthening confidence that findings were not explainable by chance," Mursu and colleagues noted.
In particular, the findings related to iron and calcium remained consistent when the analysis was restricted to follow-up from 1986 to 1996, from 1997 to 2003, and from 2004 to 2008.
In addition, the mortality risk associated with iron supplementation increased in a dose-response fashion.
The relationship was not significant for doses of 200 mg/day or less, but was significant for a dose of 201 to 400 mg/day (HR 1.35) and for a dose of 400 mg/day or more (HR 1.57).
"Iron is suggested to catalyze reactions that produce oxidants and thus promote oxidative stress," the authors noted, acknowledging that they did not examine possible mechanisms in the current study.
"However, we cannot rule out the possibility that the increase in total mortality rate was caused by illnesses for which use of iron supplements is indicated," they wrote. "Chronic disease, major injury, and/or operations may cause anemia, which is then treated with supplemental iron. However, we could find no evidence for such reverse causality."
In their commentary, Bjelakovic and Gluud said that "one should consider the likely U-shaped relationship between micronutrient status and health," with risks associated with both insufficient and excessive intake.
"Therefore, we believe that politicians and regulatory authorities should wake up to their responsibility to allow only safe products on the market," they wrote.
Added Redberg, "A better investment in health would be eating more fruits and vegetables, among other activities. Because commonly used vitamin and mineral supplements have no known benefit on mortality rate and have been shown to confer risk, this article has been given our 'Less Is More' designation."
Mursu and colleagues noted that their study was limited by the possibility of residual confounding and changes in supplement use during the study, the inability to exclude the chance that some supplements were taken in response to symptoms or clinical disease, the lack of data on nutritional status or detailed information on the supplements used, and the study sample comprised of white women, which limits the generalizability of the findings.
The study was partially supported by grants from the National Cancer Institute and the Academy of Finland, by the Finnish Cultural Foundation, and by the Fulbright program's Research Grant for a Junior Scholar.
One of Mursu's co-authors is an unpaid member of the scientific advisory board of the California Walnut Commission.
Bjelakovic and Gluud reported that they had no conflicts of interest.

Oct 13, 2008
More Vitamins Please. In the long ago days of the youth of my children our pediatrician rather naturally had us offer liquid vitamin drops daily from infancy onward. Back then it was common to find 400 to 800 IU 0f ...
May 25, 2010
Good News About Vitamins. That TV Doctor Lisa Masterson would just love you to believe her propaganda force fed to medical students and reinforced by mainstream media that all you need for good nutrition is a healthy ...
Jul 03, 2008
Fatty meals may cloud the brains of people with type 2 diabetes, but antioxidant vitamins can help clear the fog, Canadian researchers demonstrated in a study they conducted. The findings suggest, the researchers say, ...



Tuesday, March 22, 2011

If vitamins are so bad why is FDA giving them to PhRMA

Update: April 2011 - CDC: Half of US adults take vitamins, supplements


ATLANTA – About half of U.S. adults take vitamins and other dietary supplements — a level that's been holding steady for much of the past decade, new government figures show.
But the data also show a booming number of older women are taking calcium.
Federal officials released figures Wednesday showing that the use of dietary supplements has grown since the early 1990s when it was about 42 percent. The data shows use leveled off in 2003 through 2008, with about half of adults 20 and older taking at least one dietary supplement.
The biggest change was for calcium. Two-thirds of women 60 and older take it, up from 28 percent in the early 1990s.
Experts note the ranks of the elderly have been growing, and include many women who have been encouraged for years to take calcium to help protect against osteoporosis.
The information comes from national, in-home surveys in 1988-1994 and 2003-2008. The surveys in the past decade included more than 2,000 people each year. Interviewers not only asked participants what supplements they took, but also asked to see the bottles to verify their answers.
Use of multivitamins — the most popular supplement — crept up to nearly 40 percent.
Most people who take vitamins and other supplements are educated, have good incomes, eat pretty well and already get the nutrients they need from their diets, the surveys suggests.
"It's almost like the people who are taking them aren't the people who need them," said Regan Bailey, a nutritional epidemiologist with the National Institutes of Health.
Federal surveys have only recently started asking people why they take supplements, Bailey said.
The government supports some supplements as an option for certain people — such as iron for women who are pregnant, folic acid for women thinking of getting pregnant and calcium for older women.
But health officials say people should talk to their doctors first, and consider enriched foods that can accomplish the same goal.
Much of the new data is in a Centers for Disease Control and Prevention report released Wednesday. SOURCE
Online: CDC report: http://www.cdc.gov/nchs
Read more on Natural Health News

March 2011

Don’t Be a Victim of Drug Company Propaganda

It is in the economic interests of drug companies to steer Americans away from healthier lifestyles and dietary supplements. As more Americans fall ill to degenerative disease, drug company profits increase exponentially.

Enormous amounts of pharmaceutical dollars are spent influencing Congress, the FDA, and other federal agencies. The result is the promulgation of policies that cause Americans to be deprived of effective, low-cost means of protecting themselves against age-related disease.
The fact that the diets of more than 90% of Americans supply less than the 12 milligrams a day of vitamin E the government proclaims to be adequate is a startling revelation. It documents an epidemic deficiency of vitamin E among Americans who do not take supplements. Despite these grim statistics, the medical establishment continues to question the value of supplemental vitamin E. SOURCE


APRIL 2010
Help protect your right to supplements -

Alert: Protect Your Right To Natural and Bio-available Vitamin B-6!
ANH-USA On April 6, 2010 @ 3:18 pm

Human beings cannot live without vitamin B-6. It is also important for the prevention of cancer and the prevention and treatment of seizures, anemia, mental disorders including schizophrenia, carpal tunnel syndrome, and other conditions. Its effect on carpal tunnel can seem almost miraculous [1].

A natural form of the vitamin, Pyridoxamine, was recently yanked off the market by the FDA. Why? Because a pharmaceutical company, BioStratum, wanted sole use of pyridoxamine in a drug, a drug which may or may not ever appear. The company filed a so-called citizens petition and the FDA agreed, notwithstanding protests from ANH-USA, other organizations, and thousands of citizens. You might ask: how can Pharma take a supplement off the market and claim exclusive use of it as a prescription drug? The FDA does not presently feel obligated to answer this question.

Unfortunately, this isn’t all the bad news about vitamin B6. All forms of B-6, natural or synthetic, must be converted to P5P, another natural form, for the body to use it. Another drug company, Medicure Pharma, wants sole use of P5P and so has petitioned the FDA to ban its use as a supplement as well.

Medicure has yet to market a drug made from P5P, but wants the ban to take place now. And never mind that any individual unable to convert synthetic B6 to P5P would have to rely solely on Medicure’s product to stay alive.

How does Medicure think it can get away with this? Its petition states rather candidly: “Pharmaceutical companies developing new drugs must be protected from companies that may seek to market the ingredients in those drugs as dietary supplements. The marketing of such products has the potential to undermine the incentive for the development of new drugs because many people may choose to purchase the supplements rather than the drugs.”

This is not of course a case of supplement producers creating a product to compete with an existing prescription drug. It is just the reverse. P5P, the natural and bioactive form of B6, has existed in food for as long as there have been humans and has been available as a supplement for years. Medicure seems to be saying: If it seems profitable, let’s just turn a critical vitamin, one essential for human life, into a drug, make it available only by subscription, and mark up the price. This is truly outrageous.

The FDA has not yet responded to Medicure’s petition. We have asked you in the past to send a message to the FDA and Congress protesting Medicure’s P5P grab, and the time has come to send some more messages. So if you haven’t sent in a message to the FDA and Congress yet, or even if you have, please send one today [2].

[2]

While we are discussing Vitamin B6, here is the latest scientific report. An analysis of 13 U.S., European and Asian studies of vitamin B6 and colon cancer, conducted from 2002-2009, has been published in a special edition of the Journal of the American Medical Association. Studies of the range of B6 doses found that vitamin B6 taken in higher doses reduced the risk of colon cancer by 21 percent. In one study, Dr. Susanna Larsson and her colleagues at Sweden’s National Institute of Environmental Medicine reported an inverse relationship between the intake of vitamin B6 or pyridoxine and the risk of colon cancer. Dr. Larsson linked the effect to bloodstream levels of pyridoxal-phosphate (PLP), the main active coenzyme form of vitamin B6 [3]. Pyridoxal-phosphate is also known as pyridoxal 5-phosphate or (as we referred to it above) P5P.

Don’t let the FDA take away our access to the natural and most bioavailable form of B6, P5P. Please take action now [2].


--------------------------------------------------------------------------------

Article printed from Alliance for Natural Health – US: http://www.anh-usa.org

URL to article: http://www.anh-usa.org/alert-protect-your-right-to-natural-and-bio-available-vitamin-b-6/

URLs in this post:

[1] Its effect on carpal tunnel can seem almost miraculous: http://search.vitasearch.com/search?q=pyridoxine+carpal+tunnel+syndrome&restrict=Summaries&site=CP&client=CP&proxystylesheet=CP&output=xml_no_dtd&filter=0&getfields=*

[2] please send one today: https://secure3.convio.net/aahf/site/Advocacy?cmd=display&page=UserAction&id=334

[3] inked the effect to bloodstream levels of pyridoxal-phosphate (PLP), the main active coenzyme form of vitamin B6: http://www.physorg.com/print187978106.html