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Showing posts with label H5N1. Show all posts
Showing posts with label H5N1. Show all posts

Tuesday, September 29, 2009

Beware TAMIFLU

UPDATE: September 2009
Following on reports of dosing and packaging problems with children's Tamiflu, we now learn that water treatment is unable to keep your water free from another drug that may have harmful side effects.

It certainly appears that makers of Tamiflu failed to include water quality considerations as they promote their product, with problematic issues.
Tamiflu Detected in Sewage Discharge and River Water in Japan

Another Comment on Swine Flu Vax Of 2009 - Unlicensed And Untested
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Originally posted October 2005 -

For several years I have posted information on the risks of flu vaccines and medical treatment related to flu. This year (2006-present) we seem to have a high alert to drive citizens to the jab by fear more so that in the past. I would encourage you to take the following information under serious consideration.

FLU VACCINE HAS RISKS.

You can find more on leaflady.org about immunity, colds, flu, prevention and help. If you need further information send your request here: http://www.leaflady.org/feedback.htm


Human-To-Human H5N1 Transmission During Tamiflu Prophylaxis

By Dr. Henry L. Niman, PhD
Recombinomics.com

"An H5N1 influenza virus, A/Hanoi/30408/2005, was isolated on 27 February 2005 from a 14-year-old Vietnamese girl (patient 1) who had received a prophylactic dose (75mg once a day) of oseltamivir from 24 to 27 February and was given a therapeutic dose (75mg twice daily) for 7 days starting on 28 February. No virus was isolated from specimens after the administration of increased doses of oseltamivir. The patient recovered and was discharged from hospital on 14 March 2005.

The timing of infection in these two patients, together with the lack of known interaction of the girl with poultry, raises the possibility that the virus could have been transmitted from brother to sister."

The above comments from a pre-released Nature paper raise serious questions about the prophalactic use of Tamiflu and human-to-human (H2H) of H5N1. The sister, Nguyen Thi Ngoan, of the index case, Nguyen Si Tuan, was taking the FDA approved prophylactic dose of Tamiflu, 1 pill per day. However, even while on Tamiflu, she developed H5N1 bird flu symptoms. Genetic analysis of the virus suggested that she was infected by her brother, even though she was taking Tamiflu.

The above paper focuses on resistance markers in isolated clones from the sister. However, the brother and sister were part of a large case cluster of H5N1 infections. The grandfather of the two patients also tested positive for H5N1 antibodies. Although H5N1 was not isolated, it is not clear if the grandfather was taking Tamiflu when his grandson was in the hospital.

Similarly, the index case's nurse developed avian influenza. He maintained that he had no exposure to poultry, yet developed laboratory confirmed H5N1. It is not clear if the nurse was taking Tamiflu at the time of his infection.

There was a second nurse who developed bird flu symptoms. She tested negative for H5N1 by PCR. Results from serum tests were not disclosed.

The effectiveness of Tamiflu against H5N1 was also raised in in vivo mice experiments. Mice were given the equivalent of 20 pills of Tamiflu per day. This high level was justified by observations on species specific differences in metabolism. However, even after correcting for species differences, the mice were treated with an equivalent of two pills per day. However, the dose was based on treatment, even though the mice were give the drug four hours before infection. However, even with these favorable conditions, 50% of the mice died if treated for 5 days. If treated for 8 days, the percentage dead fell to 20%..These mice studies raised dosing questions for oseltamivir against H5N1. Use at the FDA approved level, priced less than ideal results.

Similarly, the cluster of human cases described above raises dosing question. The H5N1 appeared to be susceptible to a doubled dose of Tamiflu and the isolated H5n1 was sensitive to Relenza. However, nations are stockpiling Tamiflu, and the above results suggest that the FDA approved dose for prophylaxis may be inadequate.

Similarly, Tamiflu resistance is another concern. The number of H5N1 cases in Vietnam is still relatively small. It is unclear how many people in Vietnam are on Tamiflu. The identification of a Tamiflu resistant variant in the small number of people being treated is cause for concern. Similarly, prophylactic treatment in health care workers and family members may not have been sufficiently high to prevent H5N1 infections.

Thus, the proper dose of Tamiflu and the frequency of resistance in Vietnam remains unclear. Similarly, the impact of wider use of Tamiflu in Indonesia is another area of concern.

webmaster@recombinomics.com ©2005 Recombinomics. All rights reserved.
Wednesday, November 29, 2006
Tamiflu dangers reported
OTTAWA (Reuters) - Canada has asked Swiss drug maker Roche AG to warn consumers of possible health risks linked to its influenza drug Tamiflu, the health department said on Wednesday.

Ottawa took the step after receiving international reports of side-effects such as hallucinations and abnormal behavior, including self-harm. The reports include cases involving children and teenagers, primarily in Japan.

"Health Canada has requested that the manufacturer ... update the Canadian prescribing information for Tamiflu to include this new information," the department said in a statement.

According to Health Canada, there have been 84 reports as of November 11 of Canadian patients having adverse effects when using Tamiflu. Ten of those cases involved fatalities...


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Thursday, April 30, 2009

Homeopathy Effective for FLU

"Ohio reported that 24,000 cases of flu treated allopathically had a mortality rate of 28.2% while 26,000 cases of flu treated homeopathically had a mortality rate of 1.05%."

Here's a good resource for more infomation.

Read more about homeopathy and FLU

Monday, April 27, 2009

FLU: Recombinant Preparedness Alert

We suggest you consider keeping lemon and thyme essential oils for diffusion in your home and at work, you may contact us to purcahse high quality pure therapeutic essential oils. Keep adequately hydrated.

Use the SEARCH window to locate the many articles we have posted on flu and flu vaccines at Natural Health News


Swine Flu Epidemic & Avianized Flu Pandemic
Dr Bill Deagle MD DABFP AAEM A4M
4-26-9
Zoonotic Vectors of Swine and Avian Flu

The swine flu is common in the agribusiness, and antibodies to swine flu are present in 20% of vetenarians and 5% of pig farm workes, and rarely kills pigs. However, this swine flu that has presented in Mexico, Texas, California, Queens NYC, London, Italy, etc. has genes of swine, avian, human, and asian flu.

This is without any doubt a pandemic flu with a current case fatality estimated at
10% plus, and rapidly is leaping across North America and to Europe.

Since 1997, the H5N1 flu has spread to all continents. Genetics showed that six strains had high pathogenic case fatality rates in the range of 70% average from 25% to 100% case fatality rates in humans, with some clusters of human to human spread, with close physical contact.

Defiencies in two amino acids needed to allow rapid attachment to human cells was found in all strains, but can be acquired by recombinants with H9N2 or H7N3 or H3N2 etc. endemic human stains that can also coinfect pigs, birds, agricultural animals, and animals in the wild.

Until fall 2008, the avian flu did not optimally replicate unless it was at 106 degrees or higher, but now it has acquired the capacity to replicate easily at 98.6 Farhenheit.

Drug resistance to Amantadine, Tamiflu also are the predominant strains. The current swine flu is analagous to a early 20th century steamer trunk, with stickers showing the visited countries and coastal cities. It has stamps from Asia, North America, Avian, Swine and Human genetics. This is a "Lab Creation".

Now, we must understand that this virus is behaving as if it is more lethal per case that usual flu, and can recombine in pigs, wild and domestic birds, and other animals and can thus acquire PB2 deletions, NS1 gene polymorphisms, and the polybasic six amino acids that allow it to grow in brain and CNS as well as any other target organ in human and animal hosts.

The NS1 deletion of four amino acids bypasses IL4, and thus is much more lethal with massive cytokine release at end stages. Because Avian H5N1 and the 1918 Swine Flu targeted young healthy people, the release of cytokines was more violent in the most healthy.

This first wave is likely to recombine and after Phase 1 gene to population insertion, Phase 2 will result in new superstrains with additional genetic polymorphisms allow transfer efficiently to humans. Phase 2 is the bioreactor phase.

In the emergent or Phase 3, new viral Clades of Swine /Avian hybrids will then have more efficient spreading and higher spontaneous lethality.

WHO Watchdog and Author of Pandemic FLU!
Human Life International invited Dr Bill Deagle MD to speak, March 1997, to the International Board of Doctors and Scientists. After a two hour talk, the board sat me down for a presentation of a foot of documents. Included were three distinct biological programs. The first was a plasmid anti-HCG contaminated Tetanus Vaccine, to cause first trimester sterility by spontaneous induced miscarriage in the target populations of Subsharan Africa, Phillipines, and other target WHO UN high density population countries. The second program was the US Special Virus Project, with mycoplasma RNA oncogenic viruses to cause immune failure, and premature death. It was knows as the AIDS syndrome, and was a recombinant of Visna, Green Monkey and Feline leukemia retro-RNA viruses carried by host mycobacteria. Most important as the large packet of documents on the Avian Flu Project, funded by the Rothchilds and oversean by the WHO and UN. They were in process of obtaining gene fragments from deceased whalers in Alaska with the CDC and Natl Institute of Allergy and Infectious Disease, supercomputer remodeled and bioengineered resurrection of the 1918 Swine Flu. They planned to insert into the genome Avian genes and spray into Asian bird populations, which would later be a gene pool when spread was complete to all continents for a new Swine-Avian Flu Pandemic.

We now see the H1N1 flu in Mexico, Canada, UK, Italy, USA and perhaps other locations, rapidly evolving. This wave is quite lethal, but with the H5N1 genetics in the wild, it is likely to come in future waves with yet more lethal genes and more rapid spread. Certainly, in the next 7 days, the presence in multiple countries, US Pandemic Flu Alert, WHO raised from 3rd to 4th level, and the pronouncements for a decade plus of coming Pandemic Flu, this was totally a UN WHO plot to release a virus that would cull the human herd.

This is - Global 2000, NSSM 1974 population threat alerts, 1996 UN Population control documents - all calling for massive reduction in World Human Populations. Last week, the UK Prime Minister Gordon Brown called for a reduction from 60 to 30 million.

Sunday, April 26, 2009

FLU News

UPDATE: US declares public health emergency for swine flu
Tamiflu Caution
Tamiflu/Relenza Hazards
Thieves Vinegar
Millenium CF
The important thing in a pandemic: DON'T PANIC. PREPARE. BE SMART.
We encourage to to think carefully and cautiously before you consider flu vaccines. Ask questions and get all the information as required by informed consent laws. Flu vaccines have been related to greater incidence of the viruses and extremely serious side effects. We do not support vaccination as our personal choice based on the evidence. Viruses are always changing. Act to build and keep your immune system strong.

What Does The Swine Flu Outbreak Mean?
by DemFromCT (dailykos.com)
Sat Apr 25, 2009

Well, that's a loaded question, and the short answer is, we don't know yet. But here's a little that we do know about pandemics.

A pandemic is defined as: a new virus to which everybody is susceptible; the ability to readily spread from person to person; and the capability of causing significant disease in humans, said Dr. Jay Steinberg, an infectious disease specialist at Emory University Hospital Midtown in Atlanta. The new strain of swine flu meets only one of the criteria: novelty.

History indicates that flu pandemics tend to occur once every 20 years or so, so we're due for one, Steinberg said.

"I can say with 100 percent confidence that a pandemic of a new flu strain will spread in humans," he said. "What I can't say is when it will occur."

Point number one: this is a novel, never before seen virus. Humans do not have protection, though there may be some cross protection. So, that makes it dangerous and worth watching.

Point number two: we don't know anything about how easily this particular virus spreads from person to person. That's partly because we know more about the few US cases and less about the many Mexican cases. We don't know how many reported suspected cases in Mexico are actually swine flu. Only a handful of cases in Mexico have been confirmed by US and Canadian laboratories. That still leaves us with worry, but not hard fact.

Point number three: that's about how much illness it causes. In the US, not much. For Mexico:

"Public health officials in Mexico began actively looking for cases of respiratory illness upon noticing that the seasonal peak of influenza extended into April, when cases usually decline in number," the medical alert said. "They found two outbreaks of illness — one centered around Distrito Federal (Mexico City), involving about 120 cases with 13 deaths. The other is in San Luis Potosi, with 14 cases and four deaths."

Authorities also detected one death in Oaxaca, in the south, and two in Baja California Norte, near San Diego, California.

So what do the authorities say? They say this:

"Our concern has grown since yesterday in light of what we've learned since then," said Richard Besser, acting director of the CDC, during a conference call today with reporters. "This is something we're worried about and taking very seriously. We are moving quickly, being very aggressive in our approach."

and

"This has a sense of urgency about it," [William] Schaffner, chief of preventive medicine at Vanderbilt, said in a telephone interview today. "They are asking us who work in hospitals to go to our emergency rooms and our pediatric wards to gather specimens and start testing them."

But none of that means this will develop into a pandemic. It does mean we are closer now than at any time in recent memory (and it could still fizzle out. Remember, we still don't know a lot about Mexico's cases, the vast majority of which have not been analyzed.) So, as we follow the news, let's review our flu and pandemic prep advice. Here's the basics: avoidance.
~Avoid close contact. Avoid close contact with people who are sick. When you are sick, keep your distance from others to protect them from getting sick too.

~Stay home when you are sick. If possible, stay home from work, school, and errands when you are sick. You will help prevent others from catching your illness.

~Cover your mouth and nose. Cover your mouth and nose with a tissue when coughing or sneezing. It may prevent those around you from getting sick.

~Clean your hands. Washing your hands often will help protect you from germs. (Natural Health News note: Avoid using anti-bacterial soap and alcohol based hand sanitizers, use plain castile soap like Dr. Bronner's super baby mild, and keep skin lubricated with toxin-free natural lotion.)

~Avoid touching your eyes, nose or mouth. Germs are often spread when a person touches something that is contaminated with germs and then touches his or her eyes, nose, or mouth.

~Practice other good health habits. Get plenty of sleep, be physically active, manage your stress, drink plenty of fluids, and eat nutritious food.

You can always add

~Don't travel to countries in the midst of a novel flu outbreak. (of course, the official CDC advice is go, but practice 1-6).

Here's a status note from Reuters:
The experts will not necessarily issue firm recommendations on Saturday. Once more details are clear about the virus and its risks, the emergency panel could recommend a change in the WHO's pandemic alert level — currently at 3 on a scale of 1 to 6 — or recommend travel advisories to control the flu's spread.

and from Bloomberg:
The World Health Organization is set to declare the deadly swine flu virus outbreak in Mexico and the U.S. a global concern, potentially prompting travel restrictions, said a person familiar with the matter.

An emergency committee of the WHO in Geneva will declare the outbreak "a public health event of international concern" in a 4 p.m. teleconference today, said the person, who spoke on condition of anonymity because the meeting is confidential. In response, WHO Director-General Margaret Chan may raise the level of pandemic alert, which could lead to travel restrictions aimed at curbing the disease's spread.

You can take a look at the CDC and WHO visualization of how pandemics develop and are classified. Take a look, just so you're more familiar with it, as it may come up in the weeks ahead.

Along the top are the WHO phases. We are currently in phase 3, and that corresponds with the Pandemic Alert Period. Skip the USG stages because they are not widely used. At the bottom, CDC has corresponding "intervals" for the graph, and they correspond to functional "what do I do and when" information about a potential pandemic. Moving from WHO phase 3 to 4 ("you are here") means moving from CDC interval "investigation" to "recognition". That's exactly where we are — investigation. But even so, should something untoward develop there'd be time do some preparation before we moved into the "initiation" and the "acceleration" interval, even if this goes sour some time in the near future.

However, moving from investigation to recognition (i.e., WHO phase 3 to 4, or moving to the right of the big red line) would trigger all sorts of changes and alarms and trip wires in pandemic plans developed by companies and countries, and that might have an effect on travel advisories. Some multinationals might call for ex-pats to return home, just as one example. Airlines and tourism might take an economic hit (that happened to Canada during the SARS epidemic in 2003, and Canadians are still sore at WHO for acting (in their view) too precipitously in issuing travel advisories.

All this is given to give you a flavor of the complex decision making that needs to go on. WHO will be meeting in emergency session to do just that, but it's not as easy as simply saying "be cautious", not when so many factors come into play. And for a look at school closures, I refer you to this previous post when we talked about exercises and seasonal cases in Hong Kong that closed their schools.

In the meantime, we'll be tracking it here, along with the rest of the country, and we'll update periodically as needed. And if you want to know what preparations you can take, go here. get pandemic ready.

It's a site we set up with Idaho's Emergency management team exactly for that reason.

Or download this flu prep manual.

Pandemic Influenza
Preparation and Response: A Citizen's Guide

We put it there so you could. This is an excellent opportunity to think about the unthinkable. And if nothing develops, you'll be better prepped for the next natural disaster that does happen.

† † †

UPDATE
WHO warns of flu pandemic as Mexico City frets
Sat Apr 25, 2009 9:05pm BST

By Catherine Bremer and Stephanie Nebehay

MEXICO CITY/GENEVA (Reuters) - A new flu strain that has killed up to 68 people in Mexico could become a pandemic, the World Health Organisation warned on Saturday, as Mexico's crowded capital hunkered down in fear of the disease. . . .

"It has pandemic potential because it is infecting people," WHO Director-General Margaret Chan said in Geneva.

"However, we cannot say on the basis of currently available laboratory, epidemiological and clinical evidence whether or not it will indeed cause a pandemic. . . .

The new flu strain — a mixture of swine, human and avian flu viruses — is still poorly understood and the situation is evolving quickly, Chan said.

As far away as Hong Kong and Japan, health officials stepped up surveillance of travellers for flu-like symptoms, and the U.S. Centres for Disease Control and Prevention said it was actively looking for new infections in the United States.

"We are worried and because we are worried we are acting aggressively on a number of fronts," the CDC's Dr. Anne Schuchat told reporters. "The situation is serious."

Courtesy: Perelandra

Read how sauerkraut, a valuable fermented food, can help fight flu and build your immune system.